Ischemin (sodium)
| Size | Price | Stock |
|---|---|---|
| 5mg | $285 | In-stock |
| 10mg | $450 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-110315 |
| M.Wt: | 357.36 |
| Formula: | C15H16N3NaO4S |
| Purity: | >98 % |
| Solubility: | H2O : 36 mg/mL (ultrasonic;warming) |
Ischemin sodium is a CBP bromodomain inhibitor that inhibits p53 interaction with CBP and transcriptional activity in cells. Ischemin sodium salt inhibits p53-induced p21 activation with an IC50 value of 5 µM. Ischemin sodium salt also prevents apoptosis in ischemic cardiomyocytes. Ischemin sodium salt can be used in the study of cardiovascular diseases (such as myocardial ischemia)[1].
In Vitro: Ischemin sodium (50, 100 µM; 24 h) inhibits p53 activation on DNA damaging stress in U2OS cells[1].
Ischemin sodium (10 μM; 3 days) blocks apoptosis in cardiomyocytes by inhibiting caspase 3/7 activity[1].
Ischemin sodium salt inhibits p53 cellular signaling pathways in U2OS cells[1].
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Inquiry Information- Product Name:
- Ischemin (sodium)
- Cat. No.:
- HY-110315
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