Xanthine amine congener (dihydrochloride)
CAS No. : 1962928-23-9
(Synonyms: XAC (dihydrochloride))
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| Cat. No. : | HY-110303 |
| M.Wt: | 501.41 |
| Formula: | C21H30Cl2N6O4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Xanthine amine congener dihydrochloride (XAC dihydrochloride) is a potent Adenosine A1 receptor and A2 receptor antagonist with IC50 values of 1.8 and 114 nM, respectively. Xanthine amine congener acts as a convulsant agent in mice model[1]. IC50 & Target: IC50: 1.8 nM (Adenosine A1 receptor)IC50: 114 nM (Adenosine A2 receptor)[1] In Vivo: Xanthine amine congener dihydrochloride is more potent as a convulsant than either caffeine or theophyllin in infusion studies at the dosage 39.8 mg/kg. XAC has no effects by administering the drug via an i.p. injection, the seizure threshold >1000 mg/kg[1].
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