RT-AM


CAS No. : 2280796-94-1

2280796-94-1
Price and Availability of CAS No. : 2280796-94-1
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1mg $350 In-stock
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Cat. No. : HY-108715A
M.Wt: 555.49
Formula: C26H25N3O11
Purity: >98 %
Solubility: DMSO : 25 mg/mL (ultrasonic)
Introduction of 2280796-94-1 :

RT-AM is a pro-drug real thiol. Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells. In Vitro: To enhance the cell permeability of Real Thiol, the carboxylic acid groups is converted to acetoxymethyl (AM) esters, which are readily hydrolysed by esterases to regenerate Real Thiol inside cells. For cells treated with the RT-AM, real-time ratiometric images of the rapid changes of intracellular GSH concentrations in single cells can be generated by dividing the fluorescence intensity values for the 405?nm channel by the 488?nm channel at each corresponding pixel[1].

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