HSL-IN-1
CAS No. : 2095156-13-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $250 | In-stock |
| 10mg | $390 | In-stock |
| 25mg | $700 | In-stock |
| 50mg | $950 | In-stock |
| 100mg | $1750 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-101509 |
| M.Wt: | 436.58 |
| Formula: | C19H13BClF3N2O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 12.5 mg/mL (ultrasonic) |
HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability[1]. IC50 & Target:IC50: 2 nM (Hormone sensitive lipase)[1] In Vitro:HSL-IN-1 (1 μM, 30 min) exhibits high metabolic stability in rat liver microsomes[1]. In Vivo:HSL-IN-1 (3 mg/kg, p.o., single dose) exhibits potent antilipolytic effects and good oral bioavailability in male Wistar rats[1].
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