Glutaminyl Cyclase Inhibitor 3
CAS No. : 2092921-50-9
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| Cat. No. : | HY-101282 |
| M.Wt: | 468.61 |
| Formula: | C24H32N6O2S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Glutaminyl Cyclase Inhibitor 3 (compound 212 ), a designed anti-Alzheimer’s compound, is a potent human Glutaminyl Cyclase (GC) inhibitor, with an IC50 of 4.5 nM. Glutaminyl Cyclase-IN-1 (compound 212) significantly reduced the brain concentrations of pyroform Aβ and total Aβ and restored cognitive functions[1]. IC50 & Target: IC50: 4.5 nM (hGC)[1].
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