F1324
CAS No. : 2607975-44-8
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| Cat. No. : | HY-100866 |
| M.Wt: | 1765.04 |
| Formula: | C83H121N21O20S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. F1324 exhibits binding t1/2 value of 441 s and has strong inhibition activity against BCL6 PPI[1].
IC50 & Target:IC50: 1 nM (BCL6)[1]
In Vitro: F1324 binds to BCL6(5-129) with KD and IC50 values of 0.57 nM and 1 nM according to the results of an SPR analysis and cell-free ELISA assay, respectively[1].
F1324 binds BCL6 not only in cell-free but also cellbased conditions[1].
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