SCR-4026
CAS No. : 2185855-51-8
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| Cat. No. : | HY-100458 |
| M.Wt: | 311.16 |
| Formula: | C14H12Cl2N2O2 |
| Purity: | >98 % |
| Solubility: |
SCR-4026 is a neuroprotective agent with blood-brain barrier penetration ability. SCR-4026 exerts neuroprotective effects by disrupting the interaction between neuronal nNOS and PSD9, with an IC50 of 6.3 μM. SCR-4026 alleviates N-methyl-D-aspartate (NMDA)-induced excitotoxic damage in primary cortical neurons, and also protects neurons in the oxygen-glucose deprivation (OGD) model. SCR-4026 can reduce the cerebral infarct volume in the rat middle cerebral artery occlusion (MCAO) reperfusion model. SCR-4026 can be used for the study of stroke[1].
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