PKI(5-24)
CAS No. : 99534-03-9
| Size | Price | Stock |
|---|---|---|
| 1mg | $138 | In-stock |
| 5mg | $290 | In-stock |
| 10mg | $490 | In-stock |
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| 100 mg | Get quote | |
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| Cat. No. : | HY-P0222 |
| M.Wt: | 2222.38 |
| Formula: | C94H148N32O31 |
| Purity: | >98 % |
| Solubility: | H2O : 25 mg/mL (ultrasonic) |
PKI(5-24) is a potent, competitive, and synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase), with a Ki of 2.3 nM. PKI(5-24) corresponds to residues 5-24 in the naturally occurring heat-stable protein kinase inhibitor[1][2].
In Vitro:PKI(5-24) is a 20-residue peptide has been synthesized that corresponds to the active site of the skeletal muscle inhibitor protein[1].
PKI(5-24) inhibits phosphotransferase activity of the mutant cGMP kinase with higher potency than that of wild type, with Ki values of 42 μΜ and 160 μΜ, respectively[2].
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