p-Toluic acid


CAS No. : 99-94-5

(Synonyms: 4-Methylbenzoic acid)

99-94-5
Price and Availability of CAS No. : 99-94-5
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Cat. No. : HY-76547
M.Wt: 136.15
Formula: C8H8O2
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 99-94-5 :

p-Toluic acid (4-Methylbenzoic acid), coumarin, is a substituted benzoic acid. p-Toluic acidis synthetic p-aminomethylbenzoic acid (PAMBA), intermediates such as p-toluonitrile. p-Toluic acidMay have potential reproductive toxicity, press 1g/kgRepeated administration of doses can produce a variety of adverse effects on the epididymis[1][2]. IC50 & Target:AChE[2] In Vivo:In reproductive/developmental studies, p-Toluic acid (1 g/kg; po, once daily for 28 days) decreases epididymal weight and increases the incidence of oligozoospermia/azoospermia in the cauda epididymis in rats[2].
p-Toluic acid doesn't show any adverse effects on the animal's reproductive organs at doses of 0, 100, 300 or 1,000 mg/kg and doesn't affect the estrous cycle or mating performance. The NOEL for p-Toluic acid in male and female rats are considered to be 300 mg/kg[2].

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