| Size | Price | Stock |
|---|---|---|
| 500g | $27 | In-stock |
| 1000g | $53 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-76547 |
| M.Wt: | 136.15 |
| Formula: | C8H8O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
p-Toluic acid (4-Methylbenzoic acid), coumarin, is a substituted benzoic acid. p-Toluic acidis synthetic p-aminomethylbenzoic acid (PAMBA), intermediates such as p-toluonitrile. p-Toluic acidMay have potential reproductive toxicity, press 1g/kgRepeated administration of doses can produce a variety of adverse effects on the epididymis[1][2].
IC50 & Target:AChE[2]
In Vivo:In reproductive/developmental studies, p-Toluic acid (1 g/kg; po, once daily for 28 days) decreases epididymal weight and increases the incidence of oligozoospermia/azoospermia in the cauda epididymis in rats[2].
p-Toluic acid doesn't show any adverse effects on the animal's reproductive organs at doses of 0, 100, 300 or 1,000 mg/kg and doesn't affect the estrous cycle or mating performance. The NOEL for p-Toluic acid in male and female rats are considered to be 300 mg/kg[2].
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