Oxybuprocaine
CAS No. : 99-43-4
(Synonyms: Benoxinate; Novesinol; Oxybucaine)
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| 50mg | $75 | In-stock |
| 100mg | $115 | In-stock |
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| Cat. No. : | HY-B1288A |
| M.Wt: | 308.42 |
| Formula: | C17H28N2O3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 125 mg/mL |
Oxybuprocaine is a short-acting ester anesthetic. Oxybuprocaine binds to sodium channels and reversibly stabilizes neuronal membranes. Oxybuprocaine has cutaneous analgesic properties. Oxybuprocaine is less potent than Bupivacaine (HY-B0405) at producing central nervous system and cardiovascular toxicity. Oxybuprocaine can be used in ophthalmology and otolaryngology[1][2][3][4][5][6].
In Vivo:Oxybuprocaine (0.4%; topical instillation into eyes) hydrochloride ensures good conductivity and local anesthesia when applied before electrical stimulation in the maximal electroshock (MES) and 6-Hz seizure models in mice[3].
Oxybuprocaine (6.67 μmol/kg/min; i.v.) hydrochloride produces slower decreases in mean arterial blood pressure and heart rate compared with Bupivacaine (HY-B0405) in Sprague-Dawley rats, and the time to induce seizure, apnea, and impending death is longer than that of Bupivacaine[4].
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