Chelidonic acid
CAS No. : 99-32-1
| Size | Price | Stock |
|---|---|---|
| 5g | $42 | In-stock |
| 25g | $110 | In-stock |
| 50 g | Get quote | |
| 100 g | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-W041489 |
| M.Wt: | 184.10 |
| Formula: | C7H4O6 |
| Purity: | >98 % |
| Solubility: | H2O : 2.5 mg/mL (ultrasonic);DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C) |
Chelidonic acid is a component of Chelidonium majus L., used as an antimicrobial. Chelidonic acid also shows anti-inflammatory activity. Chelidonic acid has potential to inhibit IL-6 production by blocking NF-κB and caspase-1[1]. Chelidonic acid is a glutamate decarboxylase inhibitor, with a Ki of 1.2 μM[2].
IC50 & Target:Ki: 1.2 μM (Glutamate decarboxylase)[2]
NF-κB, Caspase-1[1]
In Vitro: Chelidonic acid dose-dependently decreases IL-6 production at 0.1-10 μM, inhibits expression of IL-6 mRNA at 1-10 μM[1].
Chelidonic acid (0.1-10 μM) decreases caspase-1 activation, nuclear NF-κB activation, and increases cytosol NF-κB activation[1].
Chelidonic acid is a glutamate decarboxylase inhibitor, with a Ki of 1.2 μM. Chelidonic acid does not promote formation of apoenzyme or react with free pyridoxal-P[2].
In Vivo: Chelidonic acid (0.2, 2 mg/kg p.o.) attenuates allergic reaction induced by ovalbumin in mice[3].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Chelidonic acid
- Cat. No.:
- HY-W041489
- Quantity:
Your information is safe with us.