Tricarballylic acid
CAS No. : 99-14-9
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| Cat. No. : | HY-W020215 |
| M.Wt: | 176.12 |
| Formula: | C6H8O6 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Tricarballylic acid is an orally active compound that can be produced by rumen microorganisms and has the activity of chelating magnesium. Tricarballylic acid is also a competitive inhibitor of aconitate hydratase, with a Ki value of 0.52 mM. Tricarballylic acid can inhibit the oxidation of acetate in the citric acid cycle and can be used in the research of ruminant tissue metabolism and grass tetany syndrome. In addition, Tricarballylic acid can be used to synthesize specific complexes and produce plasticizers[1][2][3][4]. IC50 & Target:Ki: 0.52 mM (aconitate hydratase)[1] In Vitro:Tricarballylic acid (0-8 mM; 0.5-1 h) can inhibit the oxidation of [14C]acetate in sheep liver slices and rat hepatocytes[1]. In Vivo:Tricarballylic acid (2%; dietary administration; 10-14 days) leads to increased urinary excretion of magnesium, calcium, and zinc, and reduces net retention of these minerals in male rats[2].
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