(R)-(+)-Bay-K-8644
CAS No. : 98791-67-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $150 | In-stock |
| 10mg | $200 | In-stock |
| 25mg | $450 | In-stock |
| 50mg | $800 | In-stock |
| 100mg | $1350 | In-stock |
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| Cat. No. : | HY-15125 |
| M.Wt: | 356.30 |
| Formula: | C16H15F3N2O4 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 300 mg/mL |
(R)-(+)-Bay-K-8644 is a calcium channel inhibitor. (R)-(+)-Bay-K-8644 inhibits Ba2+ currents (IBa) (IC50=975 nM). IC50 & Target: IC50: 975 nM (IBa)[1] In Vitro: (R)-(+)-Bay-K-8644, a conventional racemic mixture of Bay K 8644, is widely used as an L-type Ca2+ channel agonist. Each optical isomer possesses opposite effects on IBa, (R)-(+)-Bay-K-8644 as an antagonist and S(-)-Bay K 8644 as an agonist. (R)-(+)-Bay-K-8644 inhibits Ba2+ currents (IBa) (IC50=975 nM). When (R)-(+)-Bay-K-8644 (0.5 μM) is applied, IBa is suppressed to 71±10% of control. In the presence of (R)-(+)-Bay-K-8644IBa[1]. (R)-(+)-Bay-K-8644 is a calcium channel inhibitor[2].
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