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|---|---|---|
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| Cat. No. : | HY-B0563BR |
| M.Wt: | 310.86 |
| Formula: | C17H27ClN2O |
| Purity: | >98 % |
| Solubility: |
Ropivacaine (hydrochloride) (Standard) is the analytical standard of Ropivacaine (hydrochloride). This product is intended for research and analytical applications. Ropivacaine hydrochloride is a potent sodium channel blocker and blocks impulse conduction via reversible inhibition of sodium ion influx in nerve fibrese[1][2]. Ropivacaine is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane[3]. Ropivacaine is widely used for neuropathic pain management in vivo[1]. IC50 & Target:IC50: sodium ion influx[1]IC50: 402.7 μM (TREK-1 in COS-7 cell's membrane)[3]
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