Schisandrone


CAS No. : 98619-25-1

98619-25-1
Price and Availability of CAS No. : 98619-25-1
Size Price Stock
5mg $175 In-stock
10mg $240 In-stock
50 mg Get quote
100 mg Get quote
We match the lowest price on market.

We offer a substantial discount on larger orders, please inquire via [email protected]

or Fax: (86)21-58955996

Inquiry for price and availability only. Please place your order via our email or fax.

Cat. No. : HY-N2245
M.Wt: 356.41
Formula: C21H24O5
Purity: >98 %
Solubility: DMSO : ≥ 100 mg/mL
Introduction of 98619-25-1 :

Schisandrone, a 4-aryltetralone lignan, is isolated from the dried fruits of Schisandra sphenanthera[1]. Schisandrone is an alpha-hemolysin (Hla) inhibitor that downregulates the transcript levels of hla, agrA and RNAIII. Hla is an integral virulence determinant in Staphylococcus aureus that determines pathogenicity. Schisandrone is a potent inhibitor against MRSA pneumonia[2]. In Vitro:Schisandrone (4-32 µg/mL) inhibits Hla hemolytic activity without affecting the growth of S. aureus[2].
Schisandrone (4-32 µg/mL) has no apparent cytotoxicity and prevents S. aureus‑mediated A549 cell injury[2].
In Vivo:Schisandrone (40 mg/kg, s.c.) combined with antibiotic Ceftiofur exhibits a significant therapeutic effect on S. aureus infection in mice[2].

Your information is safe with us.