Eltoprazine (hydrochloride)


CAS No. : 98206-09-8

(Synonyms: DU 28853 hydrochloride)

98206-09-8
Price and Availability of CAS No. : 98206-09-8
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Cat. No. : HY-16687A
M.Wt: 256.73
Formula: C12H17ClN2O2
Purity: >98 %
Solubility: DMSO : ≥ 31 mg/mL;H2O : ≥ 100 mg/mL
Introduction of 98206-09-8 :

Eltoprazine (DU 28853) hydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine hydrochloride shows antiaggressive and anxiogenic effects[1][2]. In Vivo:Rats are chronically treated with Mianserin (10 mg/kg i.p.) or Eltoprazine (1 mg/kg i.p.) and are tested in the elevated plus-maze test for anxiety. Mianserin and Eltoprazine display opposite effects in the elevated plus-maze: Mianserin induces anxiolytic-like effects, while Eltoprazine shows anxiogenic-like ones[2].

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