BCA
CAS No. : 979-88-4
(Synonyms: Disodium bicinchoninate)
| Size | Price | Stock |
|---|---|---|
| 5g | $15 | In-stock |
| 10g | $28 | In-stock |
| 25g | $49 | In-stock |
| 100g | $146 | In-stock |
| 500g | $599 | In-stock |
| 1000g | $1198 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-15908 |
| M.Wt: | 388.29 |
| Formula: | C20H10N2Na2O4 |
| Purity: | >98 % |
| Solubility: | H2O : 100 mg/mL (ultrasonic);DMSO : 2 mg/mL (ultrasonic;warming;heat to 60°C);7.5% Sodium bicarbonate : ≥ 50 mg/mL |
BCA (Disodium bicinchoninate) is an orally active and non-competitive Beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 value of 28 µM, a Ki value of 43 µM. BCA shows anticancer activity. BCA has the potential for the research of Alzheimer's disease (AD)[1][2][3].
In Vivo:BCA (5, 15 mg/kg; i.p.; daily) inhibits tumor growth in a xenograft animal model[1].
BCA (20, 40 mg/kg; p.o.; daily for 90 days) reduces the reduction of mitochondrial biogenesis, imbalances of mitochondrial dynamics, and abnormal mitophagy caused by ovariectomy[2].
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