Neurokinin A(4-10)
CAS No. : 97559-35-8
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| Cat. No. : | HY-P0236 |
| M.Wt: | 766.91 |
| Formula: | C34H54N8O10S |
| Purity: | >98 % |
| Solubility: | 10 mM in H2O |
Neurokinin A (4-10) is a tachykinin NK2 receptor agonist. IC50 & Target: NK2 receptor[1] In Vitro: Neurokinin A (NKA) and its truncated form NKA(4-10) are potent spasmogens of human colon circular muscle, an action mediated exclusively via tachykinin NK2 receptors. A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) is performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK2 receptor in human colon circular muscle. A high density of NK2 receptors has been demonstrated in this tissue, using in vitro autoradiography and radioligand binding[1].
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