Gly-Arg-Gly-Asp-Ser
CAS No. : 96426-21-0
(Synonyms: GRGDS)
| Size | Price | Stock |
|---|---|---|
| 2mg | $60 | In-stock |
| 5mg | $108 | In-stock |
| 10mg | $168 | In-stock |
| 25mg | $264 | In-stock |
| 50mg | $400 | In-stock |
| 100mg | $600 | In-stock |
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| Cat. No. : | HY-P0295 |
| M.Wt: | 490.47 |
| Formula: | C17H30N8O9 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic);H2O : 33.33 mg/mL (ultrasonic) |
Gly-Arg-Gly-Asp-Ser (GRGDS) is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC50 of ∼5 and ∼6.5 μM[1] IC50 & Target:IC50: 5 μM (αvβ3), 6.5 μM (αvβ5)[2] In Vitro:Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3, with IC50 of 5 μM[1]. Gly-Arg-Gly-Asp-Ser-immobilized TiO2 nanotubes enhance osteoblast-like cell (MG-63) adhesion, and significantly increased cell spreading and proliferation[2].
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