Crisnatol (mesylate)
CAS No. : 96389-69-4
(Synonyms: BWA770U (mesylate))
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| Cat. No. : | HY-108999 |
| M.Wt: | 441.54 |
| Formula: | C24H27NO5S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Crisnatol (BWA770U) mesylate is an orally active and anticancer agent, and a member of the arylmethylaminopropanediol class of DNA intercalators. Crisnatol mesylate shows in vitro cytotoxicity against human breast cancer cells, but not normal human skin fibroblasts[1][2][3]. In Vitro:Crisnatol (1.3 μg/mL; 24-72 h) mesylate inhibits the replication of HepG2 cells, decreases cell viability by 35%[2]. In Vivo:Crisnatol (25 mg/kg; p.o.; single dose) mesylate shows oral activity and shows stable metabolite profile extract of rat feces by autoradiography[2].
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