Eflornithine (hydrochloride hydrate)
CAS No. : 96020-91-6
(Synonyms: DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate)
| Size | Price | Stock |
|---|---|---|
| 1g | $58 | In-stock |
| 5g | $92 | In-stock |
| 25g | $360 | In-stock |
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| Cat. No. : | HY-B0744B |
| M.Wt: | 236.64 |
| Formula: | C6H15ClF2N2O3 |
| Purity: | >98 % |
| Solubility: | H2O : 83.33 mg/mL (ultrasonic) |
Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women[1]. In Vivo:The hair growth inhibitory activity of Eflornithine is significantly enhanced when the Eflornithine cream is applied onto a mouse skin area pretreated with microneedles[3]. Treatment of coarctation hypertensive rats with Eflornithine results in a normalization of the contractile intensity to KCI and norepinephrine and relaxations to acetylcholine by 14 days of hypertension[4].
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