AGN 196996


CAS No. : 958295-17-5

958295-17-5
Price and Availability of CAS No. : 958295-17-5
Size Price Stock
5mg $270 In-stock
10mg $405 In-stock
50mg $1012 In-stock
100mg $1500 In-stock
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500 mg Get quote
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Cat. No. : HY-16682
M.Wt: 482.32
Formula: C24H20BrNO5
Purity: >98 %
Solubility: DMSO : 250 mg/mL (ultrasonic)
Introduction of 958295-17-5 :

AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM). IC50 value: 2 nM(Ki) Target: RARα antagonist AGN 196996 shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists.

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