Beclabuvir
CAS No. : 958002-33-0
(Synonyms: BMS-791325)
| Size | Price | Stock |
|---|---|---|
| 1mg | $168 | In-stock |
| 5mg | $420 | In-stock |
| 10mg | $660 | In-stock |
| 25mg | $1320 | In-stock |
| 50mg | $1920 | In-stock |
| 100mg | $2880 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-12429 |
| M.Wt: | 659.84 |
| Formula: | C36H45N5O5S |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 30 mg/mL |
Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM[1][2]. IC50 & Target:IC50: < 28 nM (NS5B protein) In Vitro:Beclabuvir demonstrates additive or synergistic antiviral activity with pegIFN/RBV and in 2- or 3-drug combinations with a range of DAAs, such as HCV NS3 protease inhibitors, NS5A inhibitors' and/or nucleoside NS5B inhibitors[2]. In Vivo:The combination of beclabuvir with asunaprevir and daclatasvir achieves very high rates of viral eradication (about 90%) in patients infected with HCV genotype 1, which is the most common genotype worldwide[1].
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Inquiry Information- Product Name:
- Beclabuvir
- Cat. No.:
- HY-12429
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