D13-9001
CAS No. : 957471-96-4
| Size | Price | Stock |
|---|---|---|
| 5mg | $1243 | In-stock |
| 10mg | $1978 | In-stock |
| 25mg | $3868 | In-stock |
| 50mg | $5994 | In-stock |
| 100mg | $9275 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-124819 |
| M.Wt: | 693.78 |
| Formula: | C31H39N11O6S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
D13-9001 is a potent AcrB (AcrAB-TolC efflux pump subunit) and MexB (MexAB-OprM efflux pump subunit) inhibitor with the KD values of 1.15 μM and 3.57 μM in E. coli and P. aeruginosa, respectively[1]. D13-9001 exhibits antibiotic activities[2].
IC50 & Target:KD: 1.15 μM (AcrB), 3.57 μM (MexB)[1]
In Vitro: D13-9001 exhibits high solubility and a good safety profile[3].
In Vivo: D13-9001 (1.25-20 mg/kg; intravenous drip infusion; 2 hours) with aztreonam (AZT) gives improved survival rates in a lethal pneumonia rats at the end of day seven compared with AZT treated alone[3].
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