7-Aminocephalosporanic acid
CAS No. : 957-68-6
(Synonyms: 7-ACA)
| Size | Price | Stock |
|---|---|---|
| 25g | $16 | In-stock |
| 100g | $49 | In-stock |
| 500g | $152 | In-stock |
| 1000g | $251 | In-stock |
| > 2 kg | Get quote | |
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| Cat. No. : | HY-B1434 |
| M.Wt: | 272.28 |
| Formula: | C10H12N2O5S |
| Purity: | >98 % |
| Solubility: | H2O : 1.1 mg/mL (ultrasonic;adjust pH to 14 with NaOH) |
7-aminocephalosporanic acid (7-ACA) is a HSP90β inhibitor and an antibiotic. 7-Aminocephalosporanic acid is the core chemical structure of the synthesis of cephalosporin antibiotics and an effective β-lactamase inhibitor[1][2].
In Vitro:7-Aminocephalosporanic acid (0-160 μM, 24 h) reduces cellular total cholesterol (TC) and triglyceride (TG) in HepG2 cells by decreasing sterol regulatory element-binding proteins (SREBPs)[2].
In Vivo:7-Aminocephalosporanic acid (5-25 mg/kg, i.p., every 2 days for 12 weeks) reduces lipid accumulation in HFD-induced obese mice[2].
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