3MB-PP1
CAS No. : 956025-83-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $100 | In-stock |
| 10mg | $180 | In-stock |
| 25mg | $360 | In-stock |
| 50mg | $570 | In-stock |
| 100mg | $920 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-102069 |
| M.Wt: | 295.38 |
| Formula: | C17H21N5 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C) |
3MB-PP1, a bulky purine analog, is a Polo-like kinase 1 (Plk1) inhibitor. 3MB-PP1 blocks mitotic progression and cell division arise through target Plk1 in in cells expressing analog-sensitive Plk1 alleles. 3MB-PP1 specifically inhibits the activity of analog-sensitive Ssn3 (Cdk8). 3MB-PP1 inhibits Leu93 Mutant Zipper-interacting protein kinase (Leu93-ZIPK; IC50=2 μM). 3MB-PP1 can be used for the research of hypha formation of Candida albicans and cell division[1][2][3]. In Vitro: 3MB-PP1 (5 μM; 3 hours) stimulates hyphal growth in a strain bearing analog-sensitive alleles of SSN3[1].
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