Colestilan
CAS No. : 95522-45-5
(Synonyms: MCI-196; Colestimide)
| Size | Price | Stock |
|---|---|---|
| 25mg | $32 | In-stock |
| 50mg | $50 | In-stock |
| 100mg | $75 | In-stock |
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| Cat. No. : | HY-112939 |
| M.Wt: | 1000.00 |
| Formula: | (C4H6N2.C3H5ClO)x |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Colestilan (MCI-196) is a non-absorbed, non-calcium-based phosphate binder and is also a non-metallic, anion exchange resin. Colestilan is orally active and can be used for hypercholesterolaemia research[1][2].
In Vitro:Colestilan (MCI-196) decreases cholesterol levels by bile acid adsorption through the gastrointestinal tract[2].
Colestilan (1 g) binds 2.52 mmol of phosphate at 2-4 mM phosphate concentration and pH = 7.2 in vitro[2].
In Vivo:Colestilan (MCI-196) (0.125 or 0.5 g content per 15 g of the feed; p.o.; 14 days) decreases blood phosphate and urinary phosphorus excretion in rats[3].
Colestilan is able to improve hyperphosphataemia in rats with renal failure induced by adenine administration for 4 weeks[1].
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