10Panx


CAS No. : 955091-53-9

955091-53-9
Price and Availability of CAS No. : 955091-53-9
Size Price Stock
1mg $40 In-stock
5mg $80 In-stock
10mg $130 In-stock
50 mg Get quote
100 mg Get quote
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Cat. No. : HY-P1137
M.Wt: 1242.34
Formula: C58H79N15O16
Purity: >98 %
Solubility: H2O : 11.11 mg/mL (adjust pH to 12 with 1 M NaOH);DMSO : 10 mg/mL (ultrasonic)
Introduction of 955091-53-9 :

10Panx is a biological active peptide. (This is a Pannexin-1 (Panx1) mimetic blocking peptide. Pannexin-1 is a recently identified membrane protein that can form gap junction-like connections allowing intercellular passage of dyes when overexpressed in two adjacent oocytes or mammalian epithelial cell lines. Blockade of pannexin-1 in macrophage endogenously expressing the ATP-gated P2X7 receptor (P2X7R) blocks the initial dye uptake, but not the ionic current, and also blocks processing and release of interleukin-1b (IL-1b) in response to P2X7R activation.)

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