5-Norbornene-2-methylamine


CAS No. : 95-10-3

(Synonyms: JBP)

95-10-3
Price and Availability of CAS No. : 95-10-3
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Cat. No. : HY-W022007
M.Wt: 123.20
Formula: C8H13N
Purity: >98 %
Solubility:
Introduction of 95-10-3 :

5-Norbornene-2-methylamine (JBP) is a hydrophobic tag. 5-Norbornene-2-methylamine serves as an E3 ligase ligand for the synthesis of PROTAC degraders, such as PROTAC PARP1 degrader-4 (HY-181460)[1]. In Vitro:5-Norbornene-2-methylamine (4 μM; 24 h) does not induce significant PARP1 degradation in MDA-MB-231 cells[1].

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