(R)-Phenylpiracetam
CAS No. : 949925-07-9
(Synonyms: MRZ 9547)
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| Cat. No. : | HY-14840A |
| M.Wt: | 218.25 |
| Formula: | C12H14N2O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
(R)-Phenylpiracetam (MRZ 9547) is a dopamine transporter (DAT) inhibitor (Ki: 14.8 μM; IC50: 65.5 μM). (R)-Phenylpiracetam can be used for the research of the neurological or neuropsychiatric disorders[1][2].
IC50 & Target: Ki: 14.8 μM (DAT); IC50: 65.5 μM (DAT)[2]
In Vitro: (R)-Phenylpiracetam displaces the binding of [125I] RTI-55 (IC50 = 4.82 μM) to human recombinant DAT expressed in CHO-K1 cells[2].
In Vivo: (R)-Phenylpiracetam (50 mg/kg; p.o. or i.p.; single-dose) reaches the mouse brain tissue 15 min after administration[1].
(R)-Phenylpiracetam (10, 25, 50 mg/kg; p.o.; pretreatment for 7 days) dose-dependently reduces paw oedema and the antinociceptive response on carrageenan induced mouse[1].
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