ALX-1393
CAS No. : 949164-09-4
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| Cat. No. : | HY-111029 |
| M.Wt: | 395.42 |
| Formula: | C23H22FNO4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
ALX-1393, a selective GlyT2 inhibitor, has an antinociceptive effect on thermal, mechanical, and chemical stimulations in a rat acute pain model[1]. IC50 & Target:GlyT2[1] In Vivo: ALX1393 (i.c.v.; 25, 50, and 100 μg) in normal rats suppresses the late-phase response in the formalin test but does not affect motor performance. ALX1393 inhibits mechanical and cold hyperalgesia in a dose-dependent manner[2].
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