Ramucirumab (anti-VEGFR)
CAS No. : 947687-13-0
| Size | Price | Stock |
|---|---|---|
| 1mg | $260 | In-stock |
| 5mg | $650 | In-stock |
| 10mg | $980 | In-stock |
| 25mg | $1800 | In-stock |
| 50mg | $2800 | In-stock |
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| Cat. No. : | HY-P9920A |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Ramucirumab (anti-VEGFR) is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab (anti-VEGFR) is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF-A, VEGF-C, and VEGF-D. Ramucirumab (anti-VEGFR) is also an angiogenesis inhibitor[1][2].
IC50 & Target:KDR
In Vitro: Ramucirumab (10 μg/mL) impedes both VEGF- and tumor-driven cord formation[3].
Ramucirumab does not cross react with mouse VEGFR2[3].
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