Salmeterol (xinafoate)
CAS No. : 94749-08-3
(Synonyms: GR 33343X xinafoate)
| Size | Price | Stock |
|---|---|---|
| 5mg | $55 | In-stock |
| 10mg | $90 | In-stock |
| 25mg | $180 | In-stock |
| 50mg | $290 | In-stock |
| 100mg | $490 | In-stock |
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| Cat. No. : | HY-17453 |
| M.Wt: | 603.75 |
| Formula: | C36H45NO7 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 50 mg/mL |
Salmeterol (GR 33343X) xinafoate is a potent and selective human β2 adrenoceptor agonist. Salmeterol shows potent stimulation of cAMP accumulation in CHO cells expressing human β2, β1 and β3 adrenoceptors with pEC50s of 9.6, 6.1, and 5.9, respectively[1]. IC50 & Target: Ki: 1.5 nM (WT β2AR)[2] In Vitro: Salmeterol (0.001-25 µM) inhibits human T lymphocyte proliferation[2]. In Vivo: Salmeterol (0.16 mg/kg), Formoterol (0.32 mg/kg) and combined treatment have therapeutic effects in mice with chronic obstructive pulmonary disease (COPD)[3].
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