Velagliflozin
CAS No. : 946525-65-1
| Size | Price | Stock |
|---|---|---|
| 1mg | $450 | In-stock |
| 5mg | $1450 | In-stock |
| 10mg | $2150 | In-stock |
| 25mg | $3650 | In-stock |
| 50mg | $5400 | In-stock |
| 100mg | $7500 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-109018 |
| M.Wt: | 395.45 |
| Formula: | C23H25NO5 |
| Purity: | >98 % |
| Solubility: | DMSO : 200 mg/mL (ultrasonic) |
Velagliflozin is an orally available sodium-glucose cotransporter 2 (SGLT2) inhibitor, with anti-diabetic activity.
IC50 & Target:SGLT2[1]
In Vitro:Velagliflozin is an oral sodium-glucose cotransporter 2 (SGLT2) inhibitor with antidiabetic activity. Velagliflozin reduces renal glucose reabsorption and stimulates glycosuria, which lowers blood sugar and insulin concentrations[1].
In Vivo:Velagliflozin (1 mg/kg; p.o.; single dose) increases cholesterol, albumin, beta-hydroxybutyrate (BHB), nonesterified fatty acids (NEFA), and urinary glucose excretion, and decreases respiratory exchange ratio in cats[1].
Velagliflozin (0.3 mg/kg; p.o.; once daily for 18 d) is well tolerated and can treat insulin disorders and prevent laminitis in ponies by reducing the high insulin response of dietary non-structural carbohydrates (NSC)[2].
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