AA29504
CAS No. : 945828-50-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $328 | Get quote |
| 10mg | $524 | Get quote |
| 25mg | $943 | Get quote |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
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| Cat. No. : | HY-103522 |
| M.Wt: | 327.42 |
| Formula: | C19H25N3O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
AA29504 is a ethyl carbamate with γ-aminobutyric acid (GABAA(HY-L120) receptor activity. AA29504 inhibits the delivery of the neurotransmitter gamma-aminobutyric acid in the central nervous system. AA29504 can be used to research anxiety, insomnia and other neuropsychiatric diseases [1].
In Vitro:AA29504 (0.1, 1, 10, 100 μM, 72 h) can open the Kv7 voltage-gated K+ channels (KCNQ) in Xenopus oocytes [1].
AA29504 (1 μM) positively regulates GABAA receptors expressed in Xenopus oocytes, EC501.4 μM[1] .
AA29504 (1 μM, 10 s) significantly enhances the gaboxadol-mediated current in pyramidal neurons of the prefrontal cortex[1].
In Vivo:AA29504 (0.5, 2 or 4 mg/kg, subcutaneously injection) has antianxiety effects in male SD (Spraguee Dawley) rats[1].
AA29504 (4 mg/kg, subcutaneous injection) significantly weakenes the motor coordination of male SD rats under the synergistic effect of alcohol [1].
AA29504 (2.5, 5 and 10 mg/kg, subcutaneously injection) has therapeutic effect on amygdala ignited seizures in male Wistar rats [1].
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