Acebilustat


CAS No. : 943764-99-6

(Synonyms: CTX-4430)

943764-99-6
Price and Availability of CAS No. : 943764-99-6
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5mg $75 In-stock
10mg $120 In-stock
25mg $250 In-stock
50mg $380 In-stock
100mg $565 In-stock
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Cat. No. : HY-17625
M.Wt: 481.54
Formula: C29H27N3O4
Purity: >98 %
Solubility: DMSO : 16.67 mg/mL (ultrasonic)
Introduction of 943764-99-6 :

Acebilustat (CTX-4430) is a leukotriene A4 hydrolase inhibitor, used for an oral antiinflammatory drug. In Vitro: Acebilustat (CTX-4430) is a leukotriene A4 hydrolase inhibitor, which is safe and well tolerated in phase 1 trial[1]. Acebilustat is an antiinflammatory drug in development for the treatment of CF and other diseases. It is a potent inhibitor of the enzyme leukotriene A4 hydrolase (LTA4H), which catalyzes the rate-limiting step in the formation of leukotriene B4 (LTB4), a potent chemoattractant and activator of inflammatory immune cells including neutrophils[2].

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