A-620223 (succinate)


CAS No. : 943650-25-7

(Synonyms: ABT-472)

943650-25-7
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Cat. No. : HY-10885
M.Wt: 404.46
Formula: C20H28N4O5
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 943650-25-7 :

A-620223 succinate (ABT-472) is an orally available poly(ADP-ribose) polymerase (PARP) inhibitor. A-620223 succinate (ABT-472) exhibits very good potency against the PARP-1 enzyme with a Ki value of 8 nM and an EC50 value of 3 nM in whole cell assay, making it useful in cancer research[1].

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