Ruxolitinib (S enantiomer)
CAS No. : 941685-37-6
(Synonyms: S-Ruxolitinib; S-INCB18424)
| Size | Price | Stock |
|---|---|---|
| 5mg | $72 | In-stock |
| 10mg | $84 | In-stock |
| 50mg | $144 | In-stock |
| 100mg | $192 | In-stock |
| 200mg | $312 | In-stock |
| 500 mg | Get quote | |
| 1 g | Get quote | |
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| Cat. No. : | HY-50856A |
| M.Wt: | 306.37 |
| Formula: | C17H18N6 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 100 mg/mL;1M HCl : 50 mg/mL (ultrasonic;adjust pH to 1 with HCl) |
Ruxolitinib (S enantiomer) (S-Ruxolitinib) is the S-enantiomer of Ruxolitinib (HY-50856). Ruxolitinib (S enantiomer) is an orally active, potent JAK inhibitor[1][2].
In Vitro:Ruxolitinib (S enantiomer) (S-Ruxolitinib; 10 μM; 12 hours) suppresses IFNβ-induced expression of ISG, IFIT, and IFITM[1].
In Vivo:Ruxolitinib (S enantiomer) (S-Ruxolitinib; 30 mg/kg; Oral gavage; twice per day separated 10-12 h for 8 weeks) reduces haematopoietic cell expansion in MPN[2].
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