Poliumoside
CAS No. : 94079-81-9
| Size | Price | Stock |
|---|---|---|
| 5mg | $86 | In-stock |
| 10mg | $148 | In-stock |
| 25mg | $312 | In-stock |
| 50mg | $506 | In-stock |
| 100mg | $820 | In-stock |
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| Cat. No. : | HY-N0033 |
| M.Wt: | 770.73 |
| Formula: | C35H46O19 |
| Purity: | >98 % |
| Solubility: | Ethanol : 50 mg/mL (ultrasonic);DMSO : 100 mg/mL (ultrasonic);H2O : 50 mg/mL (ultrasonic) |
Poliumoside, a caffeoylated phenylpropanoid glycoside, is isolated from Brandisia hancei stems and leaves. Poliumoside is an advanced glycation end product (AGE) formation and rat lens aldose reductase (RLAR) inhibitor, with IC50s of 19.69 and 8.47 μM, respectively. Poliumoside also has antiinflammatory and antioxidant activity[1][2][3].
IC50 & Target:IC50: 8.47 μM (aldose reductase)[1]
In Vitro: Poliumoside inhibits AGE formation and RLAR, with IC50s of 19.69, and 8.47 μM, respectively[1].
Poliumoside (5-30 μM; 3 h) inhibits AAPH-induced hemolysis of rat red blood cells in vitro[2].
Poliumoside (12.5-100 μM; pretreated 2 h) inhibits the release of TNF-α and IL-6 in LPS-induced RAW 264.7 cells[3].
In Vivo: Poliumoside inhibits vessel dilation in larval zebrafish[1].
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