| Size | Price | Stock |
|---|---|---|
| 25g | $9 | In-stock |
| 100g | $33 | In-stock |
| 500g | $148 | In-stock |
| 1 kg | Get quote | |
| 2 kg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-41404 |
| M.Wt: | 166.13 |
| Formula: | C8H6O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Piperonylic acid is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic Acid is a selective, mechanism-based inactivator of the trans-cinnamate 4-Hydroxylase. Piperonylic acid has anticancer, antioxidant and antibacterial activities[1][2][3][4].
In Vitro:Piperonylic acid (10 mg/mL, 24 h) has inhibitory effects on both gram-negative and gram-positive bacteria, of which S. epidermidis is the most sensitive with the MIC value is 78.12 mg/ml[3].
Piperonylic acid (50/100 μM, 24 h) ultimately promotes the growth and survival of HaCaT cells and restores cell viability after UV-induced cell damage by activating the EGFR signaling pathway[2].
Piperonylic acid (20-300 μg/mL, 60 min) has antioxidant activity and inhibits the oxidation of β-Carotene (HY-N0411) [3].
In Vivo:Piperonylic acid (20 μL of 10 μM per day, applied topically to wounds) accelerates wound healing in mice by modulating inflammation and collagen deposition[4].
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