Butamben
CAS No. : 94-25-7
(Synonyms: Butyl 4-aminobenzoate)
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|---|---|---|
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| 500g | $110 | In-stock |
| 1000g | $181 | Get quote |
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| Cat. No. : | HY-B1430 |
| M.Wt: | 193.24 |
| Formula: | C11H15NO2 |
| Purity: | >98 % |
| Solubility: | H2O : < 0.1 mg/mL;DMSO : ≥ 100 mg/mL |
Butamben (Butyl 4-aminobenzoate) results in long-lasting relief from pain, without impairing motor function or other sensory functions[1][2].
IC50 & Target: Calcium Channel[2]
Sodium Channel[3]
In Vitro: Butamben (500 μM) blocks 90% of the control barium current, and this level is reached within 4 min in PC12 cells[2].
Butamben (100 μM; 2-10 min) increases the inactivation of the fast Na+ channels, but not of the slow Na+ channels[3].
In Vivo: Butamben (0.5-50 mM; the distal portion of the tail was immersed for 2 min) has an S-shape dose-dependent analgesic activity in the radiant heat tail-flick assay of mice[4].
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