2-Ethoxybenzamide


CAS No. : 938-73-8

(Synonyms: Ethenzamide)

938-73-8
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Cat. No. : HY-B1428
M.Wt: 165.19
Formula: C9H11NO2
Purity: >98 %
Solubility: DMSO : ≥ 47 mg/mL
Introduction of 938-73-8 :

2-Ethoxybenzamide (Ethenzamide) is a nonsteroidal anti-inflammatory agent that shows analgesic and antipyretic effects. 2-Ethoxybenzamide induces melanin synthesis via cAMP response element-binding protein (CREB) phosphorylation. 2-Ethoxybenzamide can be used in the research of hypopigmentation and inflammation-related diseases[1][2]. In Vitro:2-Ethoxybenzamide (125-500 μM; 24-72 h) can increase the ROS level, enhance the expression of melanogenesis-related genes, and promote melanin synthesis in B16F1 murine melanoma cells. The mechanism involves the phosphorylation of ERK/CREB[1].

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