(E/Z)-Zotiraciclib
CAS No. : 937270-47-8
(Synonyms: (E/Z)-TG02; (E/Z)-SB1317)
| Size | Price | Stock |
|---|---|---|
| 5mg | $110 | In-stock |
| 10mg | $150 | In-stock |
| 25mg | $280 | In-stock |
| 50mg | $450 | In-stock |
| 100mg | $650 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-15166 |
| M.Wt: | 372.46 |
| Formula: | C23H24N4O |
| Purity: | >98 % |
| Solubility: | DMSO : 26.5 mg/mL (ultrasonic;warming) |
(E/Z)-Zotiraciclib ((E/Z)-TG02) is a potent inhibitor of CDK2, JAK2 and FLT3 with IC50s of 13, 73 and 56 nM, respectively. (E/Z)-Zotiraciclib effectively inhibits the proliferation of cancer cells, it can be used for the research of cancer[1][2]. IC50 & Target:IC50: 13 nM (CDK2), 73 nM (JAK2), 56 nM (FLT3)[1] In Vitro:(E/Z)-Zotiraciclib (0-10 μM) shows potent inhibition to CDK2, JAK2 and FLT3 with IC50s of 13, 73 and 56 nM, respectively[1]. (E/Z)-Zotiraciclib (0-10 μM; 48 h) inhibits proliferation of cancer cells[1]. (E/Z)-Zotiraciclib (8-1000 nM; 24 h) potently inhibits the CDK2 biomarker pRb in HCT-116 cells and potently againsts pRb in MV4-11 cells with an IC50 value of 0.13 μM[1]. In Vivo:(E/Z)-Zotiraciclib (50 and 75 mg/kg; p.o. once daily for 3 weeks) inhibits tumor growth[1]. (E/Z)-Zotiraciclib (15 and 75 mg/kg; p.o. once daily 2 days on and 5 days off; i.p. once daily 5 days on 5 days off) inhibits tumor growth in two manners[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- (E/Z)-Zotiraciclib
- Cat. No.:
- HY-15166
- Quantity:
Your information is safe with us.