OXA-01
CAS No. : 936889-68-8
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|---|---|---|
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| Cat. No. : | HY-111065 |
| M.Wt: | 409.87 |
| Formula: | C21H20ClN5O2 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
OXA-01 is a potent mTORC1 and mTORC2 inhibitor, with IC50 values of 29 nM and 7 nM, respectively[1]. In Vivo: OXA-01 demonstrated broad anti-tumor activity in several different human xenograft models of various histologies. Furthermore, in GEO and Colo-205 colon xenograft models, OXA-01 demonstrated 100% TGI, whilst rapamycin treatment resulted in only 75% and 53% TGI, respectively[1].
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