NRC-2694
CAS No. : 936446-61-6
| Size | Price | Stock |
|---|---|---|
| 5mg | $160 | In-stock |
| 10mg | $256 | In-stock |
| 25mg | $460 | In-stock |
| 50mg | $644 | In-stock |
| 100mg | $900 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-19909 |
| M.Wt: | 418.49 |
| Formula: | C24H26N4O3 |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
NRC-2694 is an epidermal growth factor receptor (EGFR) antagonist with anti-cancer and anti-proliferative properties. NRC-2694 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. In Vitro: NRC-2694 at 80 ng (190 nm) concentrations causes comparable inhibition of EGFR expression[1]. In Vivo: In toxicity studies, the maximum tolerated dose of NRC-2694 in male and female mice is 2000 mg/kg (po). NRC-2694 (10 mg/kg) regresses the tumor in mice[1].
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