PL37
CAS No. : 935481-06-4
(Synonyms: Debio-0827)
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| Cat. No. : | HY-19876 |
| M.Wt: | 518.71 |
| Formula: | C22H34N2O6S3 |
| Purity: | >98 % |
| Solubility: |
PL37 (Debio-0827) is an orally active Enkephalinase dual inhibitor (dual inhibition refers to the simultaneous inhibition of Neutral Endopeptidase and Aminopeptidase N activities). PL37 exerts its anti-hyperalgesic effects by activating μ-opioid receptors (µ-opioid receptors), with an ED50 value of 13.4 mg/kg for analgesic effects in mice. PL37 can be used to study diabetic neuropathic pain[1][2][3][4].
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