INCB16562


CAS No. : 933768-63-9

933768-63-9
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Cat. No. : HY-111077
M.Wt: 380.23
Formula: C19H11Cl2N5
Purity: >98 %
Solubility:
Introduction of 933768-63-9 :

INCB16562 is an orally active and selective inhibitor against JAK1/2 markedly selective over JAK3. INCB16562 potently inhibits interleukin-6 (IL-6)-induced phosphorylation of STAT3. Additionally, INCB16562 inhibits the proliferation and survival of myeloma cells dependent on IL-6 for growth, as well as the IL-6–induced growth of primary bone marrow-derived plasma cells. INCB16562 antagonizes the growth of myeloma xenografts in mice with antitumor activity. INCB16562 is promising for research of multiple myeloma[1].

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