Methyl Eugenol


CAS No. : 93-15-2

93-15-2
Price and Availability of CAS No. : 93-15-2
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Cat. No. : HY-N6996
M.Wt: 178.23
Formula: C11H14O2
Purity: >98 %
Solubility: H2O : < 0.1 mg/mL;DMSO : 100 mg/mL (ultrasonic)
Introduction of 93-15-2 :

Methyl Eugenol is a bait that has oral activity against oriental fruit fly (Hendel).Methyl Eugenol has anti-cancer and anti-inflammatory activities. Methyl Eugenol can induce Autophagy in cells. Methyl Eugenol can be used in the study of intestinal ischemia/reperfusion injury[1][2][3]. In Vitro:Methyl Eugenol (25% (2 mL)-100% (8 mL)) is able to trap the orange fly in a dose-dependent manner [1].
Methyl Eugenol (3.12-200 μM; 48 h) can inhibit cell proliferation (IC50=50 μM) in human retinoblastoma RB355 cells by inducing (50 μM; 24 h) autophagy and inhibiting (50 μM; 48 h) the PI3K/mTOR/Akt signaling pathway in cells[2].
Methyl Eugenol (25-100 μM) can arrest the cell cycle of RB355 cells at the G2/M phase[2].
In Vivo:Methyl Eugenol (100 mg/kg; Oral intubation; Once daily for 30 days) has anti-inflammatory effects in Wistar rats with intestinal ischemia/reperfusion injury (I/R), and can alleviate intestinal ischemia/reperfusion injury[3].

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