LUF6283
CAS No. : 92933-48-7
| Size | Price | Stock |
|---|---|---|
| 100mg | $178 | In-stock |
| 250mg | $298 | In-stock |
| 1g | $404 | In-stock |
| 5g | $2019 | Get quote |
| 10 g | Get quote | |
| 50 g | Get quote | |
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| Cat. No. : | HY-100976 |
| M.Wt: | 168.20 |
| Formula: | C8H12N2O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
LUF6283 is a potent and orally active HCA(2) partial agonist, with a Ki of 0.55 µM. LUF6283 can achieve the beneficial lipid lowering effect of niacin without producing the unwanted cutaneous flushing side effect[1]. IC50 & Target: EC50: 0.32 ± 0.06 μM (pERK1/2)[1] In Vivo: LUF6283 (C57BL/6 mice, 400 mg/kg, Oral gavage, once a day for 4 weeks) has no effect on adipose tissue ATGL/HSL expression, and significantly reduces the expression of apolipoprotein B (APOB)[1].
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