Sulfo-SMCC (sodium)
CAS No. : 92921-24-9
| Size | Price | Stock |
|---|---|---|
| 100mg | $20 | In-stock |
| 250mg | $50 | In-stock |
| 1g | $200 | In-stock |
| 5g | $687 | In-stock |
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| Cat. No. : | HY-D0975 |
| M.Wt: | 436.37 |
| Formula: | C16H17N2NaO9S |
| Purity: | >98 % |
| Solubility: | DMSO : 125 mg/mL (ultrasonic);H2O : 5 mg/mL (ultrasonic;warming;heat to 60°C) |
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively. In Vitro: The crosslinker Sulfo-SMCC consists of a maleimide and an N-hydroxysuccinimide ester group to bind to sulfhydryl groups and primary amines, respectively. Sulfo-SMCC inhibits the end-to-end annealing of stabilized Microtubules (MTs). MTs are treated with 250 μM Sulfo-SMCC, and imaged after incubation for 0 h, 6 h, and 24 h. MTs treated with Sulfo-SMCC shows a constant mean length, independent of the incubation time[1].
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